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工作简历 |
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1. 1993年8月-1996年6月:北京医科大学运动医学研究所助理研究员 Aug. 1993 - Jun. 1996: Assistant Researcher, Institute of Sports Medicine, Beijing Medical University 2. 1996年6月始-1997年9月:副研究员,住院总医师,北京医科大学运动医学研究所 Jun. 1996 - Sep. 1997: Associate Researcher & Chief Resident Doctor, Institute of Sports Medicine, Beijing Medical University 3. 1997年9月-2007年:副主任医师,北京大学运动医学研究所,北京大学第三医院 Sep. 1997-2007: Associate chief surgeon, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 4. 2002年-2003年:副教授,北京大学运动医学研究所,北京大学第三医院 2002 - 2003: Associate Professor, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 5. 2003-2006年:副所长,硕导,北京大学运动医学研究所,北京大学第三医院 2003 - 2006: Deputy Director & Master Supervisor, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 6. 2006始: 研究员,副主任医师,北京大学运动医学研究所,北京大学第三医院 2006 - 2007: Researcher & Associate chief surgeon, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 7. 2007年-2008年8月:主任医师,博导,北京大学运动医学研究所,北京大学第三医院 2007 - Aug 2008: Chief surgeon & PhD Supervisor, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 8. 2008年8月-2010年5月:Ⅲ级教授,主任医师,北京大学运动医学研究所,北京大学第三医院 Aug. 2008 - May 2010: Grade III Professor & Chief surgeon, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 9. 2010年5月-2014年9月:Ⅱ级教授,北京大学运动医学研究所,北京大学第三医院 May 2010 - Sep. 2014: Grade II Professor, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 10. 2014年9月-2015年3月:开始招收博士后研究人员,北京大学运动医学研究所,北京大学第三医院 Sep. 2014 - Mar. 2015: Supervisor for postdoctoral researchers, Institute of Sports Medicine of Peking University, Peking University 3rd Hospital 11. 2015年3月-2018年7月:北京大学第三医院教授委员会委员,北京大学运动医学研究所,北京大学第三医院 Mar. 2015 - Jul. 2018: Member of the Professor Committee, Peking University Third Hospital 12. 2018年7月26日-2019年11月26日:北京大学运动医学研究所常务副所长,北京大学第三医院运动医学膝关节外科主任,,北京大学运动医学研究所,北京大学第三医院 Jul. 26, 2018 - Nov. 26, 2019: Executive Deputy Director of the Institute of Sports Medicine, Peking University, and Director of the Knee Surgery Department, Peking University Third Hospital 13. 2019年9月-2023年11月26日:北京大学运动医学研究所所长,北京大学运动医学研究所,北京大学第三医院 Sep. 2019 - Nov. 26, 2023: Director of the Institute of Sports Medicine, Peking University. Vice Director of the Sports Medicine Department, and Director of Knee Surgery Department, Peking University Third Hospital 14. 2023年5月15日至今:清华大学附属北京清华长庚医院(清华大学临床医学院)主任医师 May 15, 2023 - Present: Chief surgeon, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University 15. 2023年6月20日至今:清华大学临床教研长聘教授、博导、博士后流动站合作教授 Jun. 20, 2023 - Present: Tenured Professor, Ph.D Supervisor, and Supervisor for Postdoctoral Researchers, School of Medicine, Tsinghua University 16. 2023年11月27日至今:清华大学附属北京清华长庚医院(清华大学临床医学院)骨科与运动医学中心主任,膝关节外科主任,清华医学骨科与运动医学研究所所长 Nov. 27, 2023 - Present: Director of the Orthopedics and Sports Medicine Center, Director of the Knee Surgery Department, Director of the Institute of Orthopedics and Sports Medicine Institute, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University 17. 2024年4月3日至今:清华大学临床医学院长聘教授委员会委员 Apr. 3, 2024 - Present: Member of the Tenured Professor Committee, School of Clinical Medicine, Tsinghua University 18. 2024年6月8日至今: 清华大学医学院教学委员会的委员 Jun. 8, 2024 – Present: Member of the Teaching Committee, School of Clinical Medicine, Tsinghua University 19. 2024年6月10日至今:清华大学医学院、清华大学人工智能学院跨学科研究生招生教授,参与清华大学体育部、清华大学五道口金融学院、清华大学工程管理硕士教育中心和清华大学医师科学家发展中心跨学科讲座和教学 Jun. 10, 2024 - Present: Interdisciplinary postgraduate supervisor at the School of Medicine, the Institute for Artificial Intelligence of Tsinghua University, has also participated in interdisciplinary lectures and teaching at the Division of Sports Science and Physical Education at Tsinghua University, the PBC School of Finance at Tsinghua University, the MEM Education Center of Tsinghua University, and the Center for Physician- Scientist Development(CPSD)of Tsinghua University 20. 2024年12月20日至今:清华大学长聘教授委员会医学组委员 Dec. 20, 2024 – Present: Member of medical group, tenured professor evaluation committee, Tsinghua University 21. 2025年1月20日至今:清华大学附属北京清华长庚医院(清华大学临床医学院)学术委员会副主席 Jan. 20, 2025 - Present: Vice Chairman, Academic Committee, Beijing Tsinghua Changgong Hospital,School of Clinical Medicine, Tsinghua University |
教学工作 |
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带教5名博士后、15名硕士研究生和39名博士研究生。 Jia-Kuo Yu had supervised 5 postdoctoral researchers, 15 master's degree candidates, and 39 doctoral degree candidates. 多名毕业博士研究生的博士论文获得学校优秀博士论文,毕业学生在毕业后的工作岗位能力出众,多人获得国自然优青、中组部青年拔尖人才、省青年拔尖人才和省杰青等称号。 Graduation papers of many graduates, under his supervision, have received the honor of Excellent graduation theses, and have demonstrated outstanding abilities in their respective workplaces after graduation, with many winning titles such as the Outstanding Youth Foundation of the National Natural Science Foundation of China, the Young Top-notch Talents Foundation of Organization Department of Central Committee of the Communist Party of China, Provincial Distinguished Young Scholars Fund, and Distinguished Professor of Cheungkong Scholar of the Ministry of Education of the People's Republic of China. 多年来培养了来自全国各地的800多名进修医,他们中有住院医、有主治医、副主任医师和主任医师,很多已经成为学科带头人、科主任和院长。余家阔积极参加边远地区高层次领军人才培养和地方特培生和学科骨干培养,他们中多数人才的培训任务来自中华人民共和国人力资源和社会保障局,多来自西藏和新疆。是新疆维吾尔自治区天池英才项目对接新疆医科大学第二附属顾客三病区支疆其关节外科和运动医学学科发展。 Till now, he has nurtured over 800 visiting physicians from diverse regions across China, encompassing residents, attending doctors, associate chief surgeons, and chief surgeons. Among them, many have ascended to positions of academic leadership, department heads, and hospital directors. He actively participated in educating high-level physicians in remote areas, local specially-trained talents, and disciplinary backbones physicians, with many training mandates from the Ministry of Human Resources and Social Security of the People's Republic of China, particularly emphasizing training physicians from the People's Government of Tibet Autonomous Region of China and training physicians from the People's Government of Xinjiang Uyghur Autonomous Region of China. He is intricately involved in the Tianchi Talent Project in People's Government of Xinjiang Uyghur Autonomous Region of China, bolstering the growth of joint surgery and sports medicine of the Second Affiliated Hospital of Xinjiang Medical University. 在多年的教学工作中,主编和副主编教材13本,相关成果获得教育部科技进步二等奖。曾获教学管理奖三等奖和教学优秀奖。 Over his teaching career, he has authored or co-authored 13 textbooks, earning him the Second Prize for Scientific and Technological Progress Awarded by the Ministry of Education of the People's Republic of China. Additionally, he has been recognized with the Third Prize for Teaching Management and the Teaching Excellence Award. 2015年11月13日在中国学位与研究生教育学会医药科工作委员会会同全国医学专业学位研究生教育指导委员会在湖北武汉召开的“医药学学位与研究生教育质量学术研讨会”上介绍研究生带教经验;2020年11月26日在北京大学第198期才斋讲堂与北京大学的同学和老师们交流了“医工交叉促进骨与关节医学技术创新发展”;2024年1月28日,在清华大学和300多名清华大学工程管理硕士交流“医工交叉、新工科和膝关节外科发展的新机遇”;2024年8月13日为国家药品监督管理局医疗器械审评专家们讲授了“智慧骨与关节外科相关产品研发介绍”课程;还参与清华大学五道口金融学院“健康中国“五期班的第三个模块“临床科学转化”主题讲座和清华大学医师科学家发展中心(CPSD)“基于骨关节伤病临床需求痛点推动科研创新转化”的课程。 On November 13, 2015, he presented his expertise in graduate student mentorship at the "Academic Seminar on the Quality of Medical Degrees and Graduate Education," jointly held in Wuhan, Hubei, by the Medicine and Pharmaceutical Sciences Working Committee of the China Degree and Graduate Education Society and the National Medical Degree Graduate Education Steering Committee. On November 26, 2020, he gave his in a thoughtful discussion on "Medicine-Engineering cross-disciplinary research Promoting Innovative Development in Bone and Joint Medicine" with students and faculty at Peking University's 198th Caizhai Lecture Hall. Furthermore, on January 28, 2024, he shared insights on "Medicine-Engineering cross-disciplinary research, Emerging Engineering Disciplines, and New Horizons for Knee Surgery Development" with over 300 Master of Engineering Management students at Tsinghua University. On August 13, 2024, he imparted knowledge on "Introduction to the Development of Intelligent Bone and Joint Surgery-Related Products" to Medical Device Reviewer of the National Medical Products Administration (NMPA). His education contributions also include participating in the " Translation of Clinical Research " themed lectures for the fifth of the "Healthy China 2030" program at Tsinghua University's PBCSF,and Tsinghua University Physician Scientist Development Center (CPSD) course on "Promoting Scientific Research Innovation and Translation Based on Clinical Needs and Pain Points in Bone and Joint Injuries." 主编和副主编膝关节外科和运动医学相关专著13部。 As the editor-in-chief and deputy editor-in-chief, Jia-Kuo Yu have compiled 13 specialized books on knee surgery and sports medicine. 是多个国内外期刊的主编、副主编、常务编委、责任编辑和编委。 He also holds positions as editor-in-chief, associate editor-in-chief, executive editorial board member, managing editor, and editorial board member for many domestic and international journals. |
研究领域 |
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1.干细胞药、组织工程支架、组织工程软骨、组织工程半月板、组织工程韧带和人工韧带及组织工程骨的研发,纳米材料、功能小分子、微环境调控、干细胞及亚群在组织再生中的作用,干细胞与再生医学相关的分子机制、干预靶点、生物信息学特征、多组学、空间转录组学、单细胞测序和类器官研究。 Research and development in mesenchymal stem cell-based drugs, scaffolds used for tissue engineering products, tissue-engineered cartilage, tissue-engineered meniscus, tissue-engineered ligaments and artificial ligaments, as well as tissue-engineered bone. Studies on the regulatory roles of nanomaterials, functional small molecules, microenvironment regulation, exosome and stem cells themself in tissue regeneration. Molecular mechanisms, intervention targets, bioinformatics characteristics, multi-omics, spatial Transcriptomics, single-cell sequencing and organoids researches related to mesenchymal stem cells and regenerative medicine. 2.膝关节骨性关节炎的分子分型、易感基因、分子机制和治疗靶点、干细胞治疗和干细胞递送系统治疗及清华大学骨关节炎天通苑自然人队列研究。微创半个性化全膝关节置换的多中心RCT研究、个性化定制3D打印人工膝关节假体的多中心研究,以及最微创个性化全膝关节置换的多中心RCT研究。全智能辅助微创全膝关节置换手术机器人研究。 Molecular classification, susceptibility genes, molecular mechanisms, and therapeutic targets of osteoarthritis. Research on stem cell therapy and stem cell delivery systems for the treatment of osteoarthritis. Also focus on the improving clinical guidelines and expert consensus in the Tsinghua University Tiantongyuan Residential Community Natural Population Cohort Study on Osteoarthritis. Multicenter RCT study on minimally invasive semi-personalized total knee replacement, multicenter study on personalized custom 3D-printed artificial knee joint prosthesis, and multicenter RCT study on the most minimally invasive personalized total knee replacement. Research on fully intelligent-assisted minimally invasive total knee replacement surgical robot. 3.膝关节前交叉韧带(ACL)和后交叉韧带(PCL)仿生解剖重建,尤其是前、后交叉韧带双束重建和全能重建手术机器人的研发及其在前、后交叉韧带双束重建和各种重建中的应用研究和多中心RCT研究。ACL和PCL同种异体和异种异体及人源化组织移植重建、交叉韧带损伤或/和重建的脑区激活相关研究、交叉韧带损伤或/和重建后的重返运动研究,交叉韧带断裂的易感基因和基因诊断研究。 Bionic anatomical reconstruction of anterior and posterior cruciate ligaments of the knee, especially in the precise positioning and accurate anatomical double-bundle reconstruction of ACL and PCL assisted by surgical robots for ACL double-bundle and all types of reconstructions. Development and Research on different graft for ACL and PCL,allograft, xenograft, as well as humanized xenograft, artificial ligament, and tissue engineered-ligament. Research on brain activation related to ligament injuries. Studies on returning to sports after ligament injury and post reconstruction. Research on susceptibility genes and genetic diagnosis for ligament ruptures. 4.损伤或切除的膝关节半月板的缝合修复或重建研究。研究用于完整半月板或部分半月板移植的同种异体半月板、异种异体半月板、半月板假体、人源化半月板移植物和组织工程半月板。研究部分半月板切除或半月板全切除后的半月板再生。 Suture repair or reconstruction of the injured or resected knee meniscus. Research on meniscus allograft, xenograft, prothesis, humanized meniscus graft and tissue engineered-meniscus for total or partial meniscus transplantation. Research on meniscus regeneration post partial meniscectomy or total meniscectomy. 5.用于膝关节软骨和软骨下骨修复和重建的自体骨软骨移植、同种异体骨软骨移植、异种异体骨软骨移植或人源化骨软骨移植。术中实时进行两名患者之间的新鲜同种异体骨软骨移植研究。自体干细胞移植用于软骨修复研究。术中原位生物3D打印修复和重建关节软骨及相关骨软骨组织研究。 Osteochondral autograft, allograft, xenograft, or humanized osteochondral graft transplantation for knee articular cartilage and subchondral bones repair and reconstructions. Intraoperative real-time fresh osteochondral allograft transplantation between patients from two operations at the same time. Autologous stem cell transplantation for cartilage repair. Intraoperative in-situ biological 3D printing repair and reconstruction for articular cartilage and related osteochondral tissue. 6.膝关节髌股关节紊乱手术适应症的临床和基础研究。研究微创全关节镜下髌骨脱位手术的新技术。髌骨脱位的家族遗传研究及其易感基因调查。研究髌股关节紊乱的易感基因诊断试剂盒和易感基因诊断新方法。 Clinical and basic research on surgical indications for patellofemoral joint disorders of the knee. Research on new surgical techniques on minimally Invasive fully arthroscopic patellar dislocation surgery. Family genetic studies on patellar dislocation and its susceptibility genes investigation. Research on genetic diagnostic kits and new methods for patellofemoral disorders’ genetic diagnosis. 7.膝关节人工智能通用大模型及其人工智能辅助垂直应用智能体的研究,用于骨关节伤病辅助诊断、辅助治疗决策、相关医学图像多模态融合、个性化医疗器械定制、术前规划、术中导航、机器人手术和术后远程智能康复垂直应用智能体研发和临床应用。 Research on artificial intelligence general large model of the knee and its artificial intelligence-assisted vertical application agents for auxiliary diagnosis, decision-making in treatment, multimodal fusion of medical images, personalized medical device customization, preoperative planning, intraoperative navigation, robotic surgery, and postoperative remote intelligent rehabilitation for bone and joint injuries and diseases. |
在研课题 |
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1. 余家阔,林源(朝阳医院)、裴征(首钢医院)和曹晓燕(纳通). 个性化定制全膝置换系统临床优势的多中心前瞻性队列研究. 项目编号:首发2022-1-4091. 北京市卫生健康委员会“首都卫生发展科研专项2022 年重点攻关项目”(Capital’s Funds for Health Improvement and Research). 资助金额90万元. 2022年1月—2024年12月. Jia-Kuo Yu, Yuan Lin (Beijing Chaoyang Hospital), Zheng Pei (Beijing Shougang Hospital), and Xiao-Yan Cao (Natong). Multicenter Prospective Cohort Study on the Clinical Advantages of a Personalized Customized Total Knee Replacement System. Project Number: Capital's Funds for Health Improvement and Research 2022-1-4091. Key Research Project of the "Capital Health Development Scientific Research Special 2022" by Beijing Municipal Health Commission. Funding Amount: 900,000 RMB. January 2022 - December 2024. 2.余家阔. 人工智能辅助的膝关节运动创伤的个性化诊断与分级治疗辅助决策系统的研究与验证. 2021年北京市自然科学基金-京津冀基础研究合作专项. 项目编号J210011. 合作单位清华大学附属北京清华长庚医院、天津医院、河北医科大学第三医院. 资助金额:60万元. 2022年1月-2024年12月. Jia-Kuo Yu. Research and Validation of an Artificial Intelligence-Assisted Personalized Diagnosis and Graded Treatment Decision Support System for Knee Joint Sports Trauma. 2021 Beijing Natural Science Foundation - Beijing-Tianjin-Hebei Basic Research Cooperation Special Project. Project Number: J210011. Collaborating Institutions: Beijing Tsinghua Changgung Hospital, Tianjin Hospital,Hebei Medical University Third Hospital. Funding Amount: 600,000 RMB. January 2022 - December 2024. 3.余家阔,王君臣,王世武,刘立波. 前交叉韧带重建手术机器人. 企业横向资助项目:委托方(甲方)北京纳通医用机器人科技有限公司;受托方(乙方)清华大学附属北京清华长庚医院;受托方(丙方)北京航空航天大学. 2022年4月16日 -2023年12月31日. 资助金额150万元. Jia-Kuo Yu, Jun-Chen Wang, Shi-Wu Wang, Li-Bo Liu. Anterior Cruciate Ligament Reconstruction Surgical Robot. Enterprise Horizontal Funding Project: Entrusting Party (Party A) Beijing Natong Medical Robot Technology Co., Ltd.; Entrusted Party (Party B) Beijing Tsinghua Changgung Hospital; Entrusted Party (Party C) Beihang University. April 16, 2022 - December 31, 2023. Funding Amount: 1,500,000 RMB. 4.余家阔,董昢. 膝关节退行性变的个性化诊断和分层治疗决策用人工智能辅助系统研究与验证. 国家自然科学基金-北京市自然科学基金区域创新联合发展基金. 资助金额:255万. 2023年1月~2026年12月. 项目批准号:U22A20283. Jia-Kuo Yu, Pei Dong. Research and Validation of an Artificial Intelligence-Assisted Personalized Diagnosis and Hierarchical Treatment Decision System for Degenerative Knee Joint Disease. National Natural Science Foundation of China - Beijing Natural Science Foundation Regional Innovation Joint Development Fund. Funding Amount: 2,550,000 RMB. January 2023 - December 2026. Project Approval Number: U22A20283. 5.余家阔,王君臣,刘立波. 膝关节前交叉韧带双束重建和全能重建手术机器人及系统的研发和临床应用. 北京市科委、中关村管委会:首都临床特色诊疗技术研究及转化应用项目. 资助金额:500万元. 2022年9月~2026年8月. 项目编号:Z221100007422013. Jia-Kuo Yu, Jun-Chen Wang, Li-Bo Liu. Development and Clinical Application of a Double-Bundle and Omnipotent Reconstruction Surgical Robot and System for Anterior Cruciate Ligament of the Knee. Beijing Municipal Science & Technology Commission, Zhongguancun Science Park Management Committee: Capital Clinical Characteristic Diagnosis and Treatment Technology Research and Transformation Application Project. Funding Amount: 5,000,000 RMB. September 2022 - August 2026. Project Number: Z221100007422013. 6.余家阔. 北京清华工业开发研究院概念验证项目. 基于人工智能的膝关节运动损伤基因智能检测与转化应用. 50万元. Jia-Kuo Yu. Concept Validation Project of Beijing Tsinghua Industrial R&D Institute. Gene Intelligent Detection and Transformation Application of Knee Joint Sports Injury Based on Artificial Intelligence. 500,000 RMB. |
科研成果 |
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1. 科技成果奖Science and Technology Achievement Award (1) 余家阔,宋长辉,杨永强,原福贞,王健,王海军,林霖,王迪,曾敬松,王安民. 个性化性别差异人工膝关节系统的关键技术发明与临床应用. 2022年度北京市科学技术奖科学技术发明奖二等奖. 2023年6月13日. 证书号:2022-F05-2-01-R01. 2023年10月31日. Jia-Kuo Yu, Song Changhui, Yang Yongqiang, Yuan Fuzhen, Wang Jian, Wang Haijun, Lin Lin, Wang Di, Zeng Jingsong, Wang Anmin. Invention of Key Technologies and Clinical Application of Personalized Gender-specific Total Knee Arthroplasty Systems. Second Prize in Beijing Technological Innovation Award. People's Government of Beijing Municipality. June 13, 2023. Certificate No. 2022-F05-2-01-R01. October 31, 2023. (2) 北京大学第三医院余家阔教授团队和纳通生物科技(北京)有限公司. 个性化设计3D打印定制人工膝关节的个性化全膝置换手术. 第6届中关村国际前沿科技创新大赛“医疗器械领域TOP10称号”. 2023年5月8日. Professor Jia-Kuo Yu's Team at Peking University Third Hospital and NaTong Biotechnology (Beijing) Co., Ltd. Personalized Total Knee Replacement Surgery with 3D-printed Customized Artificial Knees. "TOP 10 in Medical Devices", the 6th Zhongguancun International Frontier Technology Innovation Competition. May 8, 2023. (3) 余家阔,曲绵域,田得祥,于长隆,江东,龚熹,王健,王永健,王海军,林霖,刘阳,陈有荣,原福贞,许冰冰,张继英. 组织细胞微创移植和微创关节置换在治疗膝关节难治损伤中应用推广. 中华人民共和国教育部科学技术进步二等奖. 证书号:2022-440-R01. 2023年6月8日. Jia-Kuo Yu, Qu Mianyu, Tian Dexiang, Yu Changlong, Jiang Dong, Gong Xi, Wang Jian, Wang Yongjian, Wang Haijun, Lin Lin, Liu Yang, Chen Yurong, Yuan Fuzhen, Xu Bingbing, Zhang Jiying. Application and Promotion of Minimally Invasive Tissue and Cell Transplantation and Minimally Invasive Joint Replacement in the Treatment of Refractory Knee Injuries. Second Prize in Science and Technology Advancement Award, Ministry of Education of the People’s Republic of China. Certificate No. 2022-440-R01. June 8, 2023. (4) 余家阔,赵金忠,田得祥,谢敏豪,杨永强,章亚东,王飞,黄迅悟. 细胞移植组织移植人工关节植入治疗膝难治运动损伤临床研究和转化 北京大学第三医院、上海交通大学附属第六人民医院、国家体育总局运动医学研究所、华南理工大学、中国人民解放军总医院第四医学中心. 中华医学科技奖医学科学技术奖三等奖. 证书号:202003338P0801. 2021年3月10日. Jia-Kuo Yu, Zhao Jinzhong, Tian Dexiang, Xie Minhao, Yang Yongqiang, Zhang Yadong, Wang Fei, Huang Xunwu. Clinical Research and Translation of Cell Transplantation, Tissue Transplantation, and Artificial Joint Implantation for the Treatment of Refractory Sports-related Knee Injuries. Peking University Third Hospital, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, China Institute of Sport Science, South China University of Technology, The Fourth Medical Center of Chinese PLA General Hospital. Third Prize in Chinese Medical Science and Technology Award, Chinese Medical Association. Certificate No. 202003338P0801. March 10, 2021. (5) 余家阔,敖英芳,曲绵域,田得祥,王健全,崔国庆,胡跃林,江东,杨飞,姜闻博,丁建勋,张磊. 运动员膝关节半月板损伤的微创手术治疗和再生修复研究及应用推广. 中国体育科学学会科学技术奖. 一等奖. ID: KJ2018-1-01-D01. 2018年9月25日. Jia-Kuo Yu, Ao Yingfang, Qu Mianyu, Tian Dexiang, Wang Jianquan, Cui Guoqing, Hu Yuelin, Jiang Dong, Yang Fei, Jiang Wenbo, Ding Jianxun, Zhang Lei. Minimally Invasive Surgical Treatment and Regenerative Repair Research of Athlete's Meniscus Injuries of the Knee, and Its Application and Promotion. First Prize in Science and Technology Award, China Sport Science Society. NO. KJ2018-1-01-D01. September 25, 2018. (6) 余家阔,曲绵域,田得祥,敖英芳,于长隆,崔国庆,王健全,胡跃林,郑卓肇,印钰,谢兴,苗羽,徐雁,郭秦炜,王永健,陈连旭,肖健. 膝关节半月板损伤的微创手术治疗及相关研究. 2009年北京市科技进步三等奖(No.2009医-3-016). 2011年2月1日. Jia-Kuo Yu, Qu Mianyu, Tian Dexiang, Ao Yingfang, Yu Changlong, Cui Guoqing, Wang Jianquan, Hu Yuelin, Zheng Zhuozhao, Yin Yu, Xie Xing, Miao Yu, Xu Yan, Guo Qinwei, Wang Yongjian, Chen Lianxu, Xiao Jian. Minimally Invasive Surgical Treatment and Related Research on Meniscus Injuries of the Knee. Third Prize in Beijing Science and Technology Advancement Award. People's Government of Beijing Municipality. No.2009 Medicine-3-016. February 1, 2011. (7) 余家阔,王义夫,肖昊鹏,曹建国,周谋望,焦晨,程序,罗浩,杨延砚,吴同绚,刘伟,蔡巍,刘晓敏,刘宝荣. “中国射击队备战08年奥运会中运动创伤防治、提高竞技能力水平的研究及体能训练、全身皮肤电和CET在其中的应用”. 国家体育总局. 2009年5月31日. 备战2008年北京奥运会科研攻关与科技服务二等奖. ID: 2008014. Jia-Kuo Yu, Wang Yifu, Xiao Haopeng, Cao Jianguo, Zhou Mouwang, Jiao Chen, Cheng Xu, Luo Hao, Yang Yanyan, Wu Tongxuan, Liu Wei, Cai Wei, Liu Xiaomin, Liu Baorong. "Research on the Prevention and Treatment of Sports Injuries and the Improvement of Competitive Ability in Preparation for the 2008 Olympic Games by the Chinese Shooting Team, with Applications of Physical Training, Skin Conductance, and CET.". Second Prize in Scientific Research and Technology Service for the 2008 Beijing Olympic Games Preparation, China State General Administration of Sport. NO. 2008014. May 31, 2009. (8) 余家阔,曲绵域,田得祥,张美荣,宋卫民. 骨形态发生蛋白在生理性骨化和病理性骨化中的作用及临床意义研究. 中国体育科学会体育科技进步二等奖. 证书号:15. 北京:1997年11月1日. Jia-Kuo Yu, Qu Mianyu, Tian Dexiang, Zhang Meirong, Song Weimin. Research on the Role and Clinical Significance of Bone Morphogenetic Proteins in Physiological and Pathological Ossification. Second Prize in Science and Technology Advancement Award, China Sport Science Society. No. 15. November 1, 1997. (9) 余家阔第六获奖人. 国家科学技术进步奖二等奖. 中国人民解放军总医院刘玉杰,敖英芳,李众利,于长隆,王志刚,余家阔,唐佩福,郭秦炜,张群,王健全等:“骨关节训练伤微创治疗的系列研究”.证书号:2007J-J-244000-2-06-R06. 2007年12月1日. Liu Yujie, Ao Yingfang, Li Zhongli, Yu Changlong, Wang Zhigang, Jia-Kuo Yu (sixth recipient), Tang Peifu, Guo Qinwei, Zhang Qun, Wang Jianquan, et al. Series of Studies on Minimally Invasive Treatment of Training-related Musculoskeletal Injuries. Second Prize in National Science and Technology Advancement Award. No. 2007J-J-244000-2-06-R06. December 1, 2007. 2. 代表性文章Representative Articles (1) Zheng-Zheng Zhang#, You-Rong Chen#, Shao-Jie Wang#, Feng Zhao#, Xiao-Gang Wang, Fei Yang, Jin-Jun Shi, Zi-Gang Ge, Wen-Yu Ding, Yu-Chen Yang, Tong-Qiang Zou, Ji-Ying Zhang, Jia-Kuo Yu,* and Dong Jiang*. Orchestrated biomechanical, structural, and biochemical stimuli for engineering anisotropic meniscus. Sci Transl Med. 2019,11(487):eaao0750.DOI:10.1126/scitranslmed.aao0750(IF=19.3, Q1). (2) Wang SJ#, Jiang D# , Zhang ZZ# , Chen YR, Yang ZD, Zhang JY, Shi J*, Wang X*, Yu JK*. Biomimetic Nanosilica-Collagen Scaffolds for In Situ Bone Regeneration: Toward a Cell-Free, One-Step Surgery. Adv Mater. 2019, 31(49): e1904341. Doi: 10.1002/adma.201904341. Epub 2019 Oct 17. PMID: 31621958.(IF=32)(Q1). (3) Yanyu Yang#, Yatian Yang#, Yanxia Cao, Xing Wang⁎, Yourong Chen, Hongyan Liu, Yafei Gao, Jianfeng Wang, Chao Liu, Wanjie Wang⁎, Jia-Kuo Yu⁎, Decheng Wu⁎ . Anti-freezing, resilient and tough hydrogels for sensitive and large-range strain and pressure sensors. Chemical Engineering Journal 2021,403:126431. Received 20 May 2020; Received in revised form 10 July 2020; Accepted 23 July 2020; Available online 27 July 2020. Doi: 10.1016/j.cej.2020.126431(IF = 16.744)(JCR Q1). 【2022-2023-2024 Highly Cited in ESI (Essential Science Indicators)】. (4) Changhui Song#*, Lisha Liu, Zhengtai Deng, Haoyang Lei, Fuzhen Yuan, Yongqiang Yang, Yueyue Li, Jiakuo Yu*. Review Article: Research progress on the design and performance of porous titanium alloy bone implants. Journal of Materials research and technology 2023, 23: 2626-2641. Doi: https://doi.org/10.1016/j.jmrt.2023.01.155. (Q1,IF=6.4).【2024 Highly Cited in ESI (Essential Science Indicators)】 (5) Meng Yang#, Zheng-Chu Zhang#, Fu-ZhenYuan#, Rong-Hui Deng, XinYan, Feng-Biao Mao, You-Rong Chen*, Hua Lu*, Jia-KuoYu*. An immunomodulatory polypeptide hydrogel for osteochondral defect repair. Bioact Mater. 2022, 19: 678-689. (IF=18.9,Q1). Doi: 10.1016/j.bioactmat.2022.05.008.【2023 Highly Cited in ESI (Essential Science Indicators)】 (6) Bingbing Xu#, Jing Ye#, Bao-Shi Fan, Xinjie Wang, Ji-Ying Zhang, Shitang Song, Yifan Song, Wen-Bo Jian*, Xing Wang*, Jia-Kuo Yu*. Protein-spatiotemporal partition releasing gradient porous scaffolds and anti-inflammatory and antioxidant regulation remodel tissue engineered anisotropic meniscus. Bioact Mater. 2022, 20: 194-207.(IF=18.9,Q1).(January2021).doi:10.1016/j.bioactmat. 2022.05.019. 【2023 Highly Cited in ESI (Essential Science Indicators)】 (7) Chen YR#, Yan X#, Yuan FZ#, Lin L, Wang SJ, Ye J, Zhang JY, Yang M, Wu DC*, Wang X*, Yu JK*. Kartogenin-Conjugated Double-Network Hydrogel Combined with Stem Cell Transplantation and Tracing for Cartilage Repair. Adv Sci (Weinh). 2022 Oct17:e2105571. Doi: 10.1002/advs.202105571. Online ahead of print.PMID: 36253092. (IF=17.521, Q1).【2024 Highly Cited in ESI (Essential Science Indicators)】 (8) Jing Ye#, Ronghui Deng#, Xinjie Wang#, Shitang Song, Xiong Xu, Ji-Ying Zhang, Bing-Bing Xu*, Xing Wang*, Jia-Kuo Yu*. Intra-articular Histone Deacetylase Inhibitor Microcarrier Delivery to Reduce Osteoarthritis. Nano Lett. 2023 Dec 13;23(23):10832-10840. Epub 2023 Nov 27. PMID: 38009465. PMCID: PMC10722529. DOI: 10.1021/acs.nanolett.3c03037. (JCR,Q1,IF 10.1). (9) 9.RONGHUI DENG#, RUIFANG ZHAO#, ZINING ZHANG, YANG CHEN, MENG YANG, YIXUAN LIN, JING YE, NAN LI, HAO QIN, XIN YAN, JIAN SHI, FUZHEN YUAN, SHITANG SONG, ZIJIE XU, YIFAN SONG, JIANGNAN FU, BINGBING XU, GUANGJUN NIE* , AND JIA-KUO YU*. Chondrocyte membrane–coated nanoparticles promote drug retention and halt cartilage damage in rat and canine osteoarthritis. SCIENCE TRANSLATIONAL MEDICINE, 2024, 16(735):eadh9751. DOI: 10.1126/scitranslmed.adh9751. (JCR,Q1,IF 17.1). Submitted 26 March 2023. Epub 2024 Feb 21.【2024 Highly Cited in ESI (Essential Science Indicators)】. Co-BTCH. (10) Lei Liu#, Yiwen Xian#, Wantao Wang , Lin Huang, Jinghao Fan, Wenzheng Ma, Yixi Li, Hongmei Liu*, Jia-Kuo Yu*, Decheng Wu*. Meniscus-Inspired Self-Lubricating and Friction-Responsive Hydrogels for Protecting Articular Cartilage and Improving Exercise. ACS Nano 2023 Dec 12;17(23): 24308-24319. doi: 10.1021/acsnano.3c10139. Epub 2023 Nov 17. (JCR,Q1,IF 17.1). (11) Chao Li#, Ronghui Deng#, Meng Yang, Fuzhen Yuan, Chong Zhang, and Jiakuo Yu*. Advanced Hydrogel Material for Meniscus Repair. Adv. Funct. Mater. 2024, 2312276. DOI: 10.1002/adfm.202312276. (JCR,Q1,IF 18.5). (12) Jing Ye#, Yourong Chen#, Ronghui Deng#, Jiying Zhang,Hufei Wang,Shitang Song, Xinjie Wang, Bingbing Xu∗, XingWang∗, Jia-Kuo Yu∗. Robust tetra-armed poly (ethylene glycol)-based hydrogel as tissue bioadhesive for the efficient repair of meniscus tears. DOI: 10.1002/mco2.738. https://doi.org/10.1002/mco2.738. MedComm 2024; 5: e738. (JCR,Q1,IF10.7) . (13) Shao-Jie Wang#*, Rong-Hui Deng#, Chang-Hui Song#, Fu-Zhen Yuan, Peng-Qiang, Xiao-Yan Cao, Xing Wang, Lin Lin, Ji-Ying Zhang, Yu-Fang Zhu*, Jia-Kuo Yu*. Biomechanically matched and multistage hybrid porous scaffolds for stem cell-based osteochondral regeneration. Nano Today 59 (2024) 102539. doi:10.1016/j.nantod.2024.102539. (JCR,Q1,IF13.2). 3. 已经获批医疗器械注册证上市销售的研发成果转化产品介绍Introduction to new medical devices and medical equipment that have been approved for the Medical Device Registration Certificate by the National Medical Products Administration (1)为2008北京奥运医疗保障而研发,运动医学领域难治性运动损伤修复重建的重要产品,人同种异体骨-髌腱-骨和人同种异体半月板移植物两款产品的第1、2款产品 Product 1 and Product 2 used for repair and reconstructions of refractory sports injuries in the field of Sports Medicine, were specially developed for the medical supports of the 2008 Beijing Olympic Games 余家阔从1983年开始去运动队为运动员提供医疗保障,至今40多年不间断,深知奥运医疗保障的重点和难点。1987年开始和钱学森创立的中国科学技术大学近代力学系合作至今37年,一直致力于医工交叉研发新诊疗方法和装备。2001年7月14日莫斯科投票北京获得2008年举办权,两周后的7月28日,在学校的鼓励下,在德国学习运动医学和膝关节外科已满2年的余家阔为解决北京夏奥医疗保障中的难题,即万一需要,应该完成人同种异体组织移植重建奥运参赛运动员膝关节半月板和交叉韧带的结构与功能重建的保障任务。余家阔2001年从德国海德堡回国,带领团队开始研发我国首个运动创伤运动创伤和关节外科专用组织库,2003完成成果研发,2004年1月1日与企业签约开始医企协作的成果产业化。 Dr. Jia-Kuo Yu has been providing medical support for athletic teams since 1983, a span of over 40 years, giving him a deep understanding of the key challenges in Beijing 2008 Olympic medical support, i.e., allograft tendon and allograft meniscus products needed to repair and reconstruct ligament and meniscus injuries. Since 1987, Jia-Kuo Yu began to do collaborate research on biomechanics with the Department of Modern Mechanics at the University of Science and Technology of China, this department was founded by Xue-Sen Qian, from this cooperation, he dedicated himself to the cross-disciplinary research and development, it laid the foundation for the research and development of new medical devices and new medical equipment. Jia-Kuo Yu return to Beijing from Heidelberg, Germany, in 2001, to address the shortcomings in medical support system for Beijing's Summer Olympic. Specifically, Jia-Kuo Yu aimed to solve the challenge of reconstructing the structure and function of the injured meniscus and ruptured cruciate ligaments for athletes who participated in the Olympic Games in case these were needed. In 2001, Jia-Kuo Yu’s team established China's first tissue bank dedicated to sports trauma and joint surgery, completing the related research on product standard in 2003. In January 2004, he initiated hospital-enterprise cooperation to promote the industrialization of research achievements. 产品1:深低温保存的人同种异体半月板移植物和余家阔团队研发成果的第一张国家药品监督管理局三类医疗器械注册证 Product 1 and Product 2 used for repair and reconstructions of refractory sports injuries in the field of Sports Medicine, were specially developed for the medical supports of the 2008 Beijing Olympic Games 深低温保存的半月板产品的生产工艺领先国际10年,“微创类解剖人同种异体半月板移植术”的手术技术领先国际12年,余家阔团队对“微创类解剖人同种异体半月板移植术”的10-14年长期随访结果,移植半月板的生存率是94%,因此,成为国际上10年-14年,移植半月板生存率最好的团队之一。2006年半月板产品获得国家药监局深低温保存的人同种异体半月板移植物三类医疗器械注册证,该产品到目前还是国内唯一的同类产品注册证,临床应用没有不良事件报告。 The production process of cryopreserved human allograft meniscus transplants was, at that time, 10 years ahead of foreign counterparts. and the surgical techniques of minimally Invasive anatomic allograft meniscus transplantation 12 years ahead of international peers. The survival rate of the transplanted meniscus at 10-14 years of follow-up reached 94%, making the team led by Jia-Kuo Yu one of the teams with the highest long-term follow-up survival rates for meniscus transplantation globally. In 2006, the deep cryopreserved allograft meniscus product was approved Class III medical device registration certificate by the National Medical Products Administration, it was the first approved Class III medical devices registration certificate for the transformation of scientific research achievements by the team led by Jia-Kuo Yu’s team. 产品2:深低温保存的人同种异体骨髌腱骨移植物和余家阔团队研发成果的第二张国家药品监督管理局三类医疗器械注册证 Products 2: deep cryopreserved allograft human bone-patellar tendon-bone and the second Class III medical devices registration certificate of Jia-Kuo Yu’s team 2007年深低温保存的人同种异体骨-髌腱-骨获批国家药监局三类医疗器械注册证。余家阔团队在国际首发人同种异体骨-髌腱-骨双束重建膝关节前交叉韧带的成果。用双束重建的手术方式使用同种异体肌腱,解决了异体肌腱重建韧带后的失败率高和稳定性差的临床难题。 In 2007, deep cryopreserved allograft bone-patellar tendon-bone graft was approved another Class III medical device registration certificate by the National Medical Products Administration. The bone-patellar tendon-bone product resolved the clinical issues of high failure rates and poor stability associated with allograft reconstruction by innovated surgical procedure of double-bundle allograft bone patellar-tendon bone reconstruction. The long-term follow-up spanning over a decade has further substantiated that the double-bundle reconstruction of the ACL yields a lower re-rupture rate, superior anterior-posterior stability, enhanced rotational stability, and less knee joint degeneration. This further underscores the significant importance of this product in the reconstruction of knee structure and function following ACL rupture. 在2008北京奥运开幕之前完成产品上市销售,余家阔团队研发的半月板和骨-髌腱-骨产品顺利获批国家药监局三类医疗器械注册证并上市销售,为北京2008年奥运提供了上市销售的正规产品,圆满完成北京夏奥医疗保障任务,有效为国家破解了当时国外相关公司以“生物安全”为由的奥运医疗保障卡脖子难题。这两款产品至今仍是国内唯一产品,从上市至今均无临床不良事件报告。 Both of the product 1 and product 2 have already been launched on the market for sale before the opening of the 2008 Beijing Olympic Games, successfully fulfilling the medical support mission for the Beijing Summer Olympic Games and effectively overcoming the shortcoming which related foreign company informed us in 2001 that allograft meniscus and allograft bone-patellar tendon-bone products could not be sold in China due to "biosafety" concerns. These two products remain unique in China till today and have reported no clinical adverse events since they were launched on market. (2)产品3-6在触及到膝关节外科领域数字化、个性化、精准微创手术以及术后快速功能恢复的天花板。同时,它为中国快速老龄化社会中广大的全膝关节置换患者提供了具有自主知识产权的升级替代产品,该产品在设计、质量和功能上相比进口产品具有显著优势 Products 3-6 has reached the ceiling of digitalization, personalization, precision and minimally invasive surgery and rapid functional recovery in the field of Knee Surgery. Also, it provided an upgraded alternative with independent intellectual property rights for the vast number of total knee replacement patients in China's rapidly aging society, this product represents a significant advancement in design, quality, and functionality over imported counterparts. 2019年,余家阔团队完成了价值5000万元的21项专利科研成果转化。这项研究历时19年,利用3000名患者膝关节置换术前后的影像测量数据、2600例术中截骨测量数据,以及基于中国下肢数字骨库中1467例膝关节三维重建模型进行的计算机模拟全膝关节置换术中的截骨面和截骨块测量数据,解决了男女性在几何和解剖结构上的差异,有助于减少中国在骨关节手术中对进口高值耗材的高度依赖。 In 2019, Jia-Kuo Yu's team completed the scientific research achievement transformation of 21 patents worth 50 million yuan. This research and development spanned 19 years, utilizing measurements data from 3,000 patients’ pre- and post-knee replacement imaging, 2,600 intra-operative bone-cutting measurements, and osteotomy surfaces measurements and osteotomy bone blocks measurements during computer simulated total knee arthroplasty with 1467 knees’ three-dimensional reconstruction models from a digital bone bank of Chinese lower limbs. It addressed the geometric and anatomical differences between male and female, contributing to reducing China's high dependence on imported high-value consumables for bone and joint surgery. 产品3:性别特异性微创全膝关节置换假体 Product 3:Gender-Specific Minimally Invasive Total Knee Replacement knee prothesis: 2020年,首个针对全膝关节置换的性别差异性设计的人工膝关节假体获得国家药品监督管理局三类医疗器械注册证书。该假体是全球首个在股骨、聚乙烯垫和胫骨假体中全面实现性别特异性设计的假体。聚乙烯垫和胫骨假体采用大数据轮廓匹配的非对称设计,无论假体尺寸增大或减小,其性别特异性特征均与不同性别人群保持一致。相比标准膝关节假体,该性别差异性设计假体的优势包括:股骨前后径和内外径的高度的性别适配性、全球首个同时拥有宽版和窄版的男性膝关节假体、高性别适配的髌股运动仿生设计、基于大数据轮廓匹配的高性别适配的非对称设计(将胫骨截骨面的覆盖率提高了18%)、胫骨柄内外向和前后向的高性别适配性和股胫适配的性别差异设计,其他优势还包括:膝关节屈曲角度超过155°、前髁友好设计、假体边界优化以及Post-Cam接触优化。因此,性别差异性设计的全膝关节假体也被称为半个性化假体。 In 2020, the first artificial knee prosthesis with gender-specific designs for total knee replacement was approved Class III medical device registration certificate by the National Medical Devices Administration. This TKA prosthesis is the first of its kind internationally to fully incorporate gender-specific design in the femoral component, polyethylene component, and tibial component. The polyethylene component and tibial component feature an asymmetric design, and regardless of whether the prosthesis size increases or decreases, its gender-specific characteristics remain consistent with those of different gender populations. Compared with the standard knee prosthesis, the advantages of this gender-specific designed prostheses were as follows: femoral AP and ML high gender adaptation, world's first male knee prosthesis owned both wide and narrow versions, gender high fit patellofemoral motion bionics, gender high fit asymmetric design based on the big data contour matching (improved the tibial coverage rate of the tibial osteotomy surface by 18%), the high gender fit of the medial-lateral and anteroposterior position of the tibial stem, the gender difference design of femorotibial fit. Its other advantages include: the knee flexion was over 155°, the anterior condyle was friendly design, the prosthesis boundary was optimized, and its Post-Cam contact was also optimized. So, the gender-specific designed total knee prosthesis was also called semi-personalized prosthesis. 产品4-6:个性化设计的100%钴铬钼直接3D打印定制全膝关节假体(产品4)、配套定制手术导板(产品5)及专用3D打印机(产品6) Product 4-6: Personalized designed 100% CoCrMu fully direct 3D-printing customized total knee prosthesis (Product 4), its matched customized surgical guide plates (Product 5) and dedicated 3D printers (Product 6) for additive manufacturing of the Products 4 and Product 5 2012年,3D打印成为科技界的热门话题。《经济学人》4月报道称“3D打印将推动第三次工业革命”,同年10月,著名科技杂志《连线》封面文章为“3D打印机改变世界”。在此背景下,余家阔团队于2012年用3D打印机打印出全球首套人工膝关节假体。 In 2012, 3D printing emerged as a hot topic in the technology world. The Economist reported in April that "3D printing will drive the third industrial revolution." Meanwhile, the same year, famous technology magazine, Wired, featured "3D Printers Change the World" on its October cover. Against this backdrop, Dr. Jia-Kuo Yu's team printed the world's first set of artificial knee prosthesis in 2012 with 3D printer. 2013年,美国总统奥巴马在国情咨文中提出在美国建立五个新的制造中心。余家阔团队随后致力于扩大增材制造在医疗领域的大规模应用。2014年,深受2001年同种异体移植封锁的影响,余家阔作为项目负责人,获得国家自然科学基金重点仪器专项的项目支持,开发用于个性化设计的全膝关节置换假体定制的专用钴铬钼金属3D打印设备(产品6)。团队研发了特殊的上送粉式双向扑粉技术,结合新研发的双光束的平顶光斑与成形光斑原位复合技术,实现了增材制造熔池的梯度温度精准控制,是首个可以赋予人工膝关节3D打印件具有密度高、延伸率好、耐疲劳、耐磨损、耐腐蚀特性的人工关节钴铬钼增材制造专用3D打印设备。产品4-6被纳入中华人民共和国工业和信息化部首批增材制造典型应用场景名单。 In 2013, President Obama proposed in his State of the Union address to establish five new manufacturing hubs in the United States. Dr. Yu's team subsequently focused on expanding the large-scale medical applications of additive manufacturing. In 2014, deeply impacted by the allograft blockade in 2001, Dr. Yu, as the lead, supported by the National Natural Science Foundation of China for a special project to develop dedicated cobalt-chromium-molybdenum metal 3D printing equipment (Products 6) for customization of personalized designed total knee prosthesis. Jia-Kuo Yu’s team had developed a unique bidirectional powder feeding technology, which integrates dual laser beams in situ featuring flat-top and shaping spots. This achieves precise gradient temperature control in the melt pool of additive manufacturing. It is the first 3D printing process specifically for cobalt-chromium-molybdenum additive manufacturing of total knee prothesis, which endows the 3D printed prothesis possessing high density, fatigue-resistant, wear-resistant, and good corrosion-resistant properties. Product 4-6 were included in the first batch of typical additive manufacturing application scenarios by the Ministry of Industry and Information Technology of the People's Republic of China (MIIT). 2023年8月2日,当美国商用个性化膝关节假体公司仍依赖3D打印模具后铸造个性化假体时,全球首个100%钴铬钼直接3D打印股骨和胫骨假体(产品4)获得国家药品监督管理局的创新医疗器械三类医疗器械注册证书,该产品的组织密度、力学强度、抗疲劳性、耐磨性和耐腐蚀性均优于ASTM F75标准。ASTM F75是由美国材料与试验协会(ASTM)制定的标准规范,专门规定了钴铬钼(Co-Cr-Mo)合金铸件的化学成分、机械性能、微观结构等相关要求。该合金因其优异的耐磨性、耐腐蚀性和生物相容性,广泛用于医疗植入物,特别是人工关节的制造。 In August 2, 2023, while commercially available personalized knee prosthesis companies in the United States still rely on casting personalized implants after 3D printing molds, which takes very long time period, the world's first 100% CoCrMo 3D-printed femoral and tibial prosthesis(Product 4) was approval innovative Class III medical device registration certificate by the National Medical Products Administrati,the 3D printed prothesis possessed higher density, more fatigue-resistant, higher wear-resistant, and better corrosion-resistant properties than the ASTM F75. The ASTM F75 is a standard specification developed by ASTM(American Society for Testing and Materials) International, which specifically delineates the chemical composition, mechanical properties, microstructure, and other relevant requirements for cobalt-chromium-molybdenum (Co-Cr-Mo) alloy castings. This CoCrMo alloy is widely utilized in the manufacture of medical implants, particularly artificial joints, due to its excellent wear resistance, corrosion resistance, and biocompatibility. 配套个性化3D打印膝关节假体定制的个性化手术导板(产品5)获得北京市药品监督管理局的创新医疗器械二类医疗器械注册证书,这是全球首个能够完成个性化全膝关节置换所有步骤的手术导板。 The matched designed customized surgical guide plates according to the personalized knee prosthesis(Product 5) was approved innovative Class II medical device registration certificate by the Beijing Medical Products Administration, it was the world's first innovative surgical guide plates which could finish all total knee replacement surgical procedures. 从设计到手术使用,个性化3D打印全膝置换假体及其配套个性化手术导板的生产周期只有短短的15天。余家阔团队从早期的大切口全膝关节置换术,经过技术创新和改进手术操作,逐步实现了标准微创全膝关节置换术,再进步到改良型微创全膝置换术(将中国患者的微创手术适用率从4.7%提高到近100%)。更进一步,余家阔团队最终实现了性别差异性半个性化微创全膝关节置换术,并进一步发展到最微创的个性化全膝关节置换术。 From design to surgical use, the customized production cycle for personalized 3D-printed total knee replacement prosthesis and its matched designed customized surgical guide plates was shortened to 15 days. Thus, Dr. Yu's team has evolved from large-incision total knee replacement during early period, 2 years later, through technological innovation and modified surgical procedures, progress was not made to MIS. to standard minimally invasive total knee replacement, advancements were made to modified minimally invasive total knee replacement (increasing the suitability of Chinese patients for minimally invasive surgery from 4.7% to nearly 100%), more advance to gender-specific semi-personalized minimally invasive total knee replacement finally realized, and now come to the most minimally invasive personalized total knee replacement. Since performing the first large-incision total knee replacement in 2001, Dr. Yu's team has ultimately achieved the vision of minimizing total knee replacement through iterative advancements in products and surgical techniques. 自2001年完成首例大切口全膝关节置换术以来,余家阔团队通过产品和手术技术的迭代创新研发和临床应用,最终实现了全膝关节置换术创伤最小化的愿景。 Since performing the first large-incision total knee replacement in 2001, Dr. Yu's team has ultimately achieved the vision of minimizing total knee replacement through iterative advancements in products and surgical techniques. (3)智能骨关节手术领域的重要贡献(产品7、产品8和产品9) Important Contributions to the Field of Intelligent Bone and Joint Surgery (Product 7, Product 8, and Product 9) 产品7:全球首个运动损伤韧带断裂AI辅助诊断医疗器械注册证(产品7) Product 7: The World's First AI-Assisted Diagnostic Medical Device Registration Certificate for Ligament Ruptures in Sports Injury (Product 7) 2019年,受AI辅助肺结节诊断准确率超越专家的启发,余家阔团队开始探索AI在膝关节运动损伤诊断中的应用。在此过程中,余家阔团队建立了全球最大的多中心膝关节MRI数据库,新研发辅助诊断算法的灵敏度、特异性和准确率均超过96%,达到国际最高水平。2021年11月8日,即2022年冬奥会开幕前88天,该AI辅助诊断系统的服务器接入医院PACS系统,作为新冠疫情下闭环北京冬奥会医疗保障措施之一。2023年6月12日,膝关节MRI图像处理软件(医准MR)获得二类医疗器械注册证(产品7),成为全球首个运动医学ACL断裂AI辅助诊断的医疗器械注册证,标志着膝关节运动损伤诊断进入AI辅助诊断的时代。最终,ACL断裂AI诊断成果实现了转化签约。 In 2019, inspired by AI-assisted lung nodule diagnosis with accuracy superior to that of experts, Dr. Jia-Kuo Yu's team began exploring the application of AI in the diagnosis of knee joint sports injuries. During this process, they established the world's largest multi-center MRI database of knee joints. The sensitivity, specificity, and accuracy of the newly developed diagnostic algorithm, all exceeding 96%, representing the highest international standards. On November 8, 2021, 88 days before the 2022 Winter Olympics, the server of this AI-assisted diagnostic system was connected to the hospital's PACS system as one of the measures to ensure medical support for the closed-loop Beijing Winter Olympics amidst the COVID-19 pandemic. On June 12, 2023, the Knee MRI Image Processing Software (Yizhun MR) was approved Class II medical device registration certificate ( Product 7), making it the world's first medical device registration certificate for AI-assisted diagnosis of ACL ruptures in sports medicine. This marks the advancement of knee sports injury diagnosis into a new era of AI-assisted diagnosis. Finally the AI diagnostic achievement for ACL ruptures achieved the signing of achievement transformation. 产品8:ACL双束重建和全能重建的独特导航产品 Product 8: Unique navigation products for ACL double-bundle reconstruction and almighty reconstructions 传统的ACL(前交叉韧带)重建导航系统只能粗略定位骨道位置,缺乏膝关节的详细信息采集,例如关节软骨、ACL的股骨和胫骨足迹。作为全球首个能够进行ACL双束重建和几乎所有单束重建及翻修重建的导航系统,该导航软件基于CT和MRI成像多模态融合建模的领先注册技术,可为医生提供高精度导航和丰富的骨隧道位置选择的数据支持。 Traditional ACL ( anterior cruciate ligament )reconstruction navigation systems can only roughly locate the bone tunnel position and lack detailed information collections on the knee joint, for example the articular cartilage, the femoral and tibial footprints of the ACL. As the world's first navigation system capable of performing ACL double-bundle reconstruction and almost all kinds of single-bundle reconstruction and revision reconstruction, this navigation software features leading registration technology base on CT and MRI imaging multi-modal fusion modeling. It provides doctors with high-precision navigation and rich data support for bone tunnel position selection. 在术前规划过程中,系统进行CT和MR图像的多模态配准和融合,精确重建包括骨骼、半月板、关节软骨和ACL股骨及胫骨足迹的3D模型,并显示其他关键组织信息,如外侧髁间嵴、膝关节屈伸时移植物与髁间窝顶的撞击测试,以及膝关节屈伸时移植物的等长状态测试。 Firstly, in the preoperative process, the system performs multimodal registration and fusion of CT and MR images, accurately reconstructing 3D models including bone, meniscus, articular cartilage and femoral and tibial footprints of the ACL. It can also display other key tissue information such as lateral intercondylar ridge, impingement test between the graft and the roof of the intercondylar notch during knee flexion and extension, and the isometric state of the graft during the flexion and extension of the knee joint could also be tested. 在术前规划中,骨道可根据B&H(Bernard-Hertel)四格表和预设的股骨及胫骨道自动生成,并计算其他骨道信息,如骨道长度、骨道直径、骨道中心轴与胫骨平台的角度、双束重建用双双骨道之间的骨桥厚度以及移植物弯曲角度(GBA)。 In preoperative planning, bone tunnels can be automatically generated according to the B&H (Bernard-Hertel) fourfold table and preset femoral and tibial tunnels. It also calculates other bone tunnel information, such as tunnel length, tunnel diameter, angle between the central axis of the bone tunnel with the tibial plateau, bone bridge gap between the double bundles, and the graft bending angle (GBA). 在手术过程中,系统采用点云法进行配准。医生使用球头探针采集患者软骨表面数据,而不会损伤患者原有的健康软骨表面。采集的点云数据与术前规划中带软骨面和软骨下骨的三维建模进行配准,这是通过导航独特的球头探针点云配准算法实现的。该导航创新性地解决了ACL重建手术中小切口、探针采集范围有限和探针角度受限的问题。 During the intraoperative process, the system uses a point cloud method for registration. The surgeon uses a ball-tip probe to collect data on the patient's cartilage surface without damaging the patient's original healthy cartilage surface. The collected point cloud data is registered with the model reconstructed in the preoperative system with cartilage surfaces and subchondral bone. This is achieved through the system's unique ball-tip probe point cloud registration algorithm. The system innovatively solves the problems of small incisions, limited probe collection range, and restricted probe angles in ACL reconstruction surgery. 在移植物评估模块中,导航可以采集患者的真实运动姿态,实现膝关节骨道和移植物的全维度动态姿态显示;移植物等长分析功能为等长ACL重建技术提供了重要的附着点选择参考。此外,导航系统还可以对ACL体格检查中的Lachman试验和轴移试验进行数据测量,为ACL重建前后膝关节稳定性的定量分析提供了丰富而真实的数据支持。 In the graft evaluation module, the system can collect the patient's real motion posture, allowing for full-dimensional dynamic posture display of the knee joint bone tunnel and graft. The graft isometric analysis function provides important attachment point references for isometric ACL reconstruction techniques. Additionally, the system conducts data measurements for the Lachman test and pivot shift test in the physical examination of the ACL, providing real data support for quantitative analysis of stability before and after ACL reconstruction. 产品9:全球首个双束和全能重建前交叉韧带重建手术机器人 Product 9: The World's First Surgical Robot for Double-Bundle and Omnipotent Anterior Cruciate Ligament Reconstructions 世纪之交的2000年12月8日,在德国巴登-符腾堡州拉施塔特,余家阔与德国导师Hans H. Paessler教授与机器人比赛进行了一场ACL重建手术比赛。作为第一助手,余家阔协助Paessler教授在25分钟内完成了术者亲自手术,精度与耗时2.5小时的机器人相同,最终Paessler教授和余家阔赢得了比赛。 At the turn of the century, on December 8, 2000, in Rastatt, Baden-Württemberg, Germany, Dr. Jia-Kuo Yu and his German mentor Professor Hans H. Paessler, performed a manual anterior cruciate ligament (ACL) reconstruction surgery in competition with a robot. With Dr. Yu as the first assistant, Professor Paessler completed the surgery in 25 minutes with the same accuracy as the robot, which took 2.5 hours, ultimately Professor Hans H. Paessler and Jia-Kuo Yu won the competition. 2016年,余家阔使用进口ACL重建导航系统尝试进行导航下ACL重建,但在手术中仅定位胫骨隧道就花费了两小时,最终因手术时间过长而放弃导航方法,转为常规手术。为解决这些临床挑战,2023年,余家阔团队与企业签订了ACL双束和全能重建机器人的技术委托开发合同,并签署了产品预转让合同。经过严格开发的ACL重建机器人于2024年9月19日获得国家药品监督管理局的三类医疗器械注册证,并由合作企业迅速实现产业化和市场化。 In 2016, Dr. Yu used an imported ACL reconstruction navigation system, try to do ACL reconstruction under navigation. However, during the surgery, it took him two hours just to position the tibial tunnel, prompting him to abandon the navigation method and switch to a conventional surgery due to the excessive surgical duration. To address these clinical challenges, in 2023, Dr. Yu's team signed a technology commissioning contract with company for the cooperative R&D of the ACL reconstruction robots for both double-bundle and omnipotent reconstructions, they signed a pre-transfer contract for the developed product. The ACL reconstruction robot, which underwent rigorous development, was approved Class III Medical Device Registration Certificate of the National Medical Products Administration on September 19, 2024, and was subsequently industrialized and marketed by the collaborating enterprise. 这标志着ACL重建手术,运动创伤手术的典型代表手术,进入了智能机器人手术的时代。该手术机器人是全球首个利用CT和MRI图像多模态融合建模进行术前规划和术中导航,并能够完成精准ACL双束重建、各类单束重建及翻修ACL重建的手术机器人。它也是首个基于原生ACL附着点实现精确快速导航定位的机器人,同时是全球首个双束ACL重建机器人,也是中国唯一获得国家药品监督管理局三类医疗器械注册证书的ACL精确重建机器人。 This marked the entrance of ACL reconstruction surgery, a typical representative of sports trauma surgeries, into a new era of intelligent robotic surgeries. This surgical robot is the world's first to utilize multi-modal fusion modeling of CT and MRI images for preoperative planning and intraoperative navigation, and could complete precise double-bundle ACL reconstruction, all kinds of single-bundle, and revision ACL reconstructions. It is also the first to achieve precise and rapid navigation and positioning based on the native ACL insertion points. Furthermore, it is the first double-bundle ACL reconstruction robot globally and the only ACL precise reconstruction robot in China to obtain a Class III Medical Device Registration Certificate of the National Medical Products Administration. 4. 主编或副主编的专著Books of of Editor-in-Chief and Associate Editor-in-Chief (1) 主编. 《中国当代医学名家经典手术(二期)-“膝关节软骨损伤治疗”--常见软骨修复手术》. 2014年度国家出版基金支持项目、“十二五”国家重点出版规划项目. 韩启德院士在该项目中作为名誉主任委员.是国家新闻出版总置、国家卫健委、总后卫生部、中华医学会、中国医师协会、中国口腔医学会共同支持的项目. 人民军医出版社:2015年9月第一版. 中英文双语. I S B N:978-7-9004-9684-3. Editor-in-Chief: Jia-Kuo Yu. Chinese Contemporary Famous Surgeons' Classic Surgeries (Phase II) - "Treatment of Knee Cartilage Injuries" - Common Cartilage Repair Surgeries. Supported by the 2014 National Publishing Funding and the "Twelfth Five-Year Plan" National Key Publishing Program. Academician Han Qide served as the Honorary Director of the project. This project was jointly supported by the State Press and Publication Administration, the National Health Commission of the People's Republic of China, the Health Department of the General Logistics Department of the PLA, the Chinese Medical Association, the Chinese Medical Doctor Association, and the Chinese Stomatological Association. People's Military Medical Publishing House: First Edition, September 2015. Bilingual in Chinese and English. ISBN: 978-7-9004-9684-3. (2) 余家阔主译. 见韩鸿宾、余家阔和王福生主译《骨骼肌肉MRI/CT断层解剖》(第三版). [美] 艾里·克豪里Georges Y. El-Khoury, William J. Montgomery和Ronald A. Bergman原著《Sectional anatomy by MRI and CT》. 北京大学医学出版社. 2009年4月第三版. I S B N:978-7-81071-745-8. Translator-in-Chief: Jia-Kuo Yu. Sectional Anatomy by MRI and CT (Third Edition), translated by Han Hongbin, Jia-Kuo Yu, and Wang Fusheng. Originally authored by Georges Y. El-Khoury, William J. Montgomery, and Ronald A. Bergman (USA). Peking University Medical Press: Third Edition, April 2009. ISBN: 978-7-81071-745-8. (3) 余家阔主译. 《骨科的生物治疗》. 原著:Alberto Gobbi, Joāo Espregueira-Mendes, John G. Lane, Mustafa Karahan的《Bio-orthopaedics: a new approach》. 主译:付维力,李箭,周宗科,余家阔. 2022年8月第一版. 392页. 北京:北京大学医学出版社. I S B N :978-7-56592-4-279. Translator-in-Chief: Jia-Kuo Yu. Bio-orthopaedics: A New Approach. Translated by Fu Weili, Li Jian, Zhou Zongke, and Jia-Kuo Yu. Originally authored by Alberto Gobbi, João Espregueira-Mendes, John G. Lane, and Mustafa Karahan. First Edition, August 2022. Peking University Medical Press. ISBN: 978-7-56592-4-279. (4) 余家阔副主编. 见于长隆主编《常见运动创伤的护理和康复》. 副主编:余家阔,陈秀云. 北京大学医学出版社. 2007年5月第一版. 45.5万字. 本书由华夏英才基金资助出版,是华夏英才基金学术文库丛书. I S B N:7-81071-935-1. Associate Editor-in-Chief: Jia-Kuo Yu. Nursing and Rehabilitation of Common Sports Injuries, edited by Yu Changlong. Associate Editors: Jia-Kuo Yu and Chen Xiuyun. Peking University Medical Press: First Edition, May 2007. 455,000 characters. Supported by the Huaxia Talent Fund and part of the Huaxia Talent Fund Academic Library Series. ISBN: 7-81071-935-1. (5) 余家阔副主编.见刘玉杰主编《膝关节韧带损伤修复与重建》. 主编:刘玉杰,敖英芳,陈世益. 副主编:薛静,余家阔,孙磊. 人民卫生出版社. 2008年第一版. I S B N :978-7-117-10723-5. Associate Editor-in-Chief: Jia-Kuo Yu. Repair and Reconstruction of Knee Ligament Injuries, edited by Liu Yujie, Ao Yingfang, and Chen Shiyi. Associate Editors: Xue Jing, Jia-Kuo Yu, and Sun Lei. People's Medical Publishing House: First Edition, 2008. ISBN: 978-7-117-10723-5. (6) 余家阔副主编. 见敖英芳主编《运动创伤手术操作与技巧》. 副主编:胡跃林,崔国庆,余家阔,王健全. 2008年1月第一版. 北京:人民卫生出版社. 40.2万字. I S B N:978-7-117-09616-4. Associate Editor-in-Chief: Jia-Kuo Yu. Surgical Operations and Techniques in Sports Injuries, edited by Ao Yingfang. Associate Editors: Hu Yuelin, Cui Guoqing, Jia-Kuo Yu, and Wang Jianquan. People's Medical Publishing House: First Edition, January 2008. 402,000 characters. ISBN: 978-7-117-09616-4. (7) 余家阔副主编. 见关骅和张光铂主编《中国骨科康复学》. 副主编:余家阔,郭险峰,洪毅,郭龙. 人民军医出版社. 2011年5月第一版. 133万字. 北京. I S B N:978-7-5091-4364-3. Associate Editor-in-Chief: Jia-Kuo Yu. Chinese Orthopedic Rehabilitation, edited by Guan Hua and Zhang Guangbo. Associate Editors: Jia-Kuo Yu, Guo Xianfeng, Hong Yi, and Guo Long. People's Military Medical Publishing House: First Edition, May 2011. 1,330,000 characters. Beijing. ISBN: 978-7-5091-4364-3. (8) 余家阔副主编. 见敖英芳主编《关节镜外科学》. 副主编:胡跃林,余家阔,徐国庆,王健全. 北京大学医学出版社. 国家十一五重点图书. 2012年9月第一版. 128.6万字. I S B N:978-7-5659-0400-4. Associate Editor-in-Chief: Jia-Kuo Yu. Arthroscopic Surgery, edited by Ao Yingfang. Associate Editors: Hu Yuelin, Jia-Kuo Yu, Xu Guoqing, and Wang Jianquan. Peking University Medical Press: National Eleventh Five-Year Plan Key Book. First Edition, September 2012. 1,286,000 characters. ISBN: 978-7-5659-0400-4. (9) 余家阔副主编. 见刘玉杰主编《膝关节韧带损伤修复与重建》(第二版).主编:刘玉杰,敖英芳,陈世益. 副主编:孙磊,余家阔,薛静,王俊良. I S B N :978-7-117-18499-1. 人民卫生出版社. 2014年5月第二版. Associate Editor-in-Chief: Jia-Kuo Yu. Repair and Reconstruction of Knee Ligament Injuries (Second Edition), edited by Liu Yujie, Ao Yingfang, and Chen Shiyi. Associate Editors: Sun Lei, Jia-Kuo Yu, Xue Jing, and Wang Junliang. People's Medical Publishing House: Second Edition, May 2014. ISBN: 978-7-117-18499-1. (10) 余家阔副主译. 见韩鸿宾等主译:《骨骼肌肉MRI/CT断层解剖(第四版)》. 原著:Mark W. Anderson, Michael G.Fox主编《Sectional anatomy by MRI and CT》. 副主译:张卫光,余家阔,王福生,阎军浩. 2019年6月第四版. 1210千字. 北京:北京大学医学出版社. ISBN:978-7-5659-1759-2. Associate Translator-in-Chief: Jia-Kuo Yu. Sectional Anatomy by MRI and CT (Fourth Edition), translated by Han Hongbin et al. Associate Translators: Zhang Weiguang, Jia-Kuo Yu, Wang Fusheng, and Yan Junhao. Originally authored by Mark W. Anderson and Michael G. Fox. Fourth Edition, June 2019. 1,210,000 characters. Peking University Medical Press. ISBN: 978-7-5659-1759-2. (11) 余家阔副主编. 见国家体育总局冬季运动管理中心编著《中国冰雪项目运动伤病防治—国家队队医培训教材》. 主编:崔国庆. 副主编:谢敏豪,余家阔,胡跃林,庞晓峰,李璟,王天兵,矫玮,周方,张辛,常翠青,罗浩. 2022年1月第一版. 622千字. 北京:中国计划出版社. I S B N:978-7-5182-1380-1. Associate Editor-in-Chief: Jia-Kuo Yu. Prevention and Treatment of Sports Injuries in China's Winter Sports Programs - Training Textbook for National Team Doctors. Edited by Cui Guoqing. Associate Editors: Xie Minhao, Jia-Kuo Yu, Hu Yuelin, Pang Xiaofeng, Li Jing, Wang Tianbing, Jiao Wei, Zhou Fang, Zhang Xin, Chang Cuiqing, and Luo Hao. First Edition, January 2022. 622,000 characters. Beijing: China Planning Press. ISBN: 978-7-5182-1380-1. (12) 余家阔副主编. 见邱贵兴等主编《骨骼肌肉现代康复学》(上册).主编:邱贵兴,洪毅,唐佩福,蒋协远. 副主编:刘克敏,张军卫,余家阔,陈亚平,刘宝戈,姚浩群,苏彦农,郭险峰,姜春岩,崔国庆,陈学明,赵宇. I S B N :15BN978-7-80237-9466. 1856千字,73印张. 军事科学出版社. 2023年7月第一版. Associate Editor-in-Chief: Jia-Kuo Yu. Modern Rehabilitation of Musculoskeletal System (Upper Volume), Edited by Qiu Guixing, Hong Yi, Tang Peifu, and Jiang Xieyuan. Associate Editors: Liu Kemin, Zhang Junwei, Jia-Kuo Yu, Chen Yaping, Liu Baoge, Yao Haoqun, Su Yannong, Guo Xianfeng, Jiang Chunyan, Cui Guoqing, Chen Xueming, and Zhao Yu. ISBN: 978-7-80237-9466. 1,856,000 characters, 73 printed sheets. Military Science Press: First Edition, July 2023. (13) 余家阔副主编. 见邱贵兴等主编《骨骼肌肉现代康复学》(下册).主编:邱贵兴,洪毅,唐佩福,蒋协远. 副主编:刘克敏,张军卫,余家阔,陈亚平,刘宝戈,姚浩群,苏彦农,郭险峰,姜春岩,崔国庆,陈学明,赵宇. I S B N :15BN978-7-80237-9466. 1856千字,73印张. 军事科学出版社. 2023年7月第一版. Associate Editor-in-Chief: Jia-Kuo Yu. Modern Rehabilitation of Musculoskeletal System (Lower Volume), Edited by Qiu Guixing, Hong Yi, Tang Peifu, and Jiang Xieyuan. Associate Editors: Liu Kemin, Zhang Junwei, Jia-Kuo Yu, Chen Yaping, Liu Baoge, Yao Haoqun, Su Yannong, Guo Xianfeng, Jiang Chunyan, Cui Guoqing, Chen Xueming, and Zhao Yu. ISBN: 978-7-80237-9466. 1,856,000 characters, 73 printed sheets. Military Science Press: First Edition, July 2023.
余家阔团队致力于膝关节损伤的精准诊断及其微创结构和功能重建已有40余年。通过专注于新型诊断和治疗方法的研究,以及创新医疗器械和医疗装备的研发、科技成果转化与产业化及其临床应用推广,他们在该领域取得了显著的技术突破和广泛认可的治疗效果。 Jia-Kuo Yu’s team has dedicated over 40 years to precise diagnose knee injuries and to practice their minimally invasive structural and functional reconstructions. By focusing on novel diagnostic and therapeutic methods, as well as research and development innovative medical devices and medical equipment, and science and technology achievements transformations and industrializations, and their clinical application promotion, they have achieved significant technological breakthroughs and widely recognized therapeutic effects in this field. 这些新技术和医疗器械及医疗装备在临床诊断和治疗中的普及应用,使膝关节伤病诊疗的临床水平和科研水平在国际上居于领先地位,尤其在运动医学领域的膝关节伤病的组织移植及损伤区域的结构功能重建方面,在运动医学领域处于领先地位;经过数十年跟随国际全膝关节置换术的发展趋势,余家阔团队如今在人工膝关节假体的个性化设计、定制化增材制造和微创个性化手术的关节外科领域占据了领先地位;AI辅助诊断和智能手术机器人的临床应用,将余家阔团队推向了智慧骨与关节外科领域的国际前沿。 The popularization and application of these new techniques and medical devices into clinical diagnosis and treatment has placed the clinical level and scientific research level of knee surgery at the forefront in the field of knee tissue transplantation and reconstruction of injured structures and functions of the knee in Sports Medicine field. After decades of following international trends in total knee arthroplasty, Jia-Kuo Yu’s team has now taken a leading position in personalized design of artificial knee prosthesis, customized additive manufacturing techniques, and minimally invasive surgeries in the field of Knee Surgery. The clinical application of AI-assisted diagnosis and intelligent surgical robots has propelled Jia-Kuo Yu’s team to the international forefront in the field of Intelligent Bone and Joint Surgery. 同行们相信,这些创新、研发,以及越来越多新研发的新型医疗器械和设备,将在国内外运动医学、膝关节外科和智慧骨与关节外科的创新实践中发挥关键作用。 Peers are convinced that these innovations, these researches and developments, and these more and more new medical devices and equipment, will play a pivotal role in guiding innovative practices in Sports Medicine, Knee surgery and Intelligent Bone and Joint Surgery both domestically and internationally. |
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1. 主编. 《中国当代医学名家经典手术(二期)-“膝关节软骨损伤治疗”--常见软骨修复手术》. 2014年度国家出版基金支持项目、“十二五”国家重点出版规划项目. 韩启德院士在该项目中作为名誉主任委员.是国家新闻出版总置、国家卫健委、总后卫生部、中华医学会、中国医师协会、中国口腔医学会共同支持的项目. 人民军医出版社:2015年9月第一版. 中英文双语. I S B N:978-7-9004-9684-3. Editor-in-Chief: Jia-Kuo Yu. Chinese Contemporary Famous Surgeons' Classic Surgeries (Phase II) - "Treatment of Knee Cartilage Injuries" - Common Cartilage Repair Surgeries. Supported by the 2014 National Publishing Funding and the "Twelfth Five-Year Plan" National Key Publishing Program. Academician Han Qide served as the Honorary Director of the project. This project was jointly supported by the State Press and Publication Administration, the National Health Commission of the People's Republic of China, the Health Department of the General Logistics Department of the PLA, the Chinese Medical Association, the Chinese Medical Doctor Association, and the Chinese Stomatological Association. People's Military Medical Publishing House: First Edition, September 2015. Bilingual in Chinese and English. ISBN: 978-7-9004-9684-3. 2. 余家阔主译. 见韩鸿宾、余家阔和王福生主译《骨骼肌肉MRI/CT断层解剖》(第三版). [美] 艾里·克豪里Georges Y. El-Khoury, William J. Montgomery和Ronald A. Bergman原著《Sectional anatomy by MRI and CT》. 北京大学医学出版社. 2009年4月第三版. I S B N:978-7-81071-745-8. Translator-in-Chief: Jia-Kuo Yu. Sectional Anatomy by MRI and CT (Third Edition), translated by Han Hongbin, Jia-Kuo Yu, and Wang Fusheng. Originally authored by Georges Y. El-Khoury, William J. Montgomery, and Ronald A. Bergman (USA). Peking University Medical Press: Third Edition, April 2009. ISBN: 978-7-81071-745-8. 3. 余家阔主译. 《骨科的生物治疗》. 原著:Alberto Gobbi, Joāo Espregueira-Mendes, John G. Lane, Mustafa Karahan的《Bio-orthopaedics: a new approach》. 主译:付维力,李箭,周宗科,余家阔. 2022年8月第一版. 392页. 北京:北京大学医学出版社. I S B N :978-7-56592-4-279. Translator-in-Chief: Jia-Kuo Yu. Bio-orthopaedics: A New Approach. Translated by Fu Weili, Li Jian, Zhou Zongke, and Jia-Kuo Yu. Originally authored by Alberto Gobbi, João Espregueira-Mendes, John G. Lane, and Mustafa Karahan. First Edition, August 2022. Peking University Medical Press. ISBN: 978-7-56592-4-279. 4. 余家阔副主编. 见于长隆主编《常见运动创伤的护理和康复》. 副主编:余家阔,陈秀云. 北京大学医学出版社. 2007年5月第一版. 45.5万字. 本书由华夏英才基金资助出版,是华夏英才基金学术文库丛书. I S B N:7-81071-935-1. Associate Editor-in-Chief: Jia-Kuo Yu. Nursing and Rehabilitation of Common Sports Injuries, edited by Yu Changlong. Associate Editors: Jia-Kuo Yu and Chen Xiuyun. Peking University Medical Press: First Edition, May 2007. 455,000 characters. Supported by the Huaxia Talent Fund and part of the Huaxia Talent Fund Academic Library Series. ISBN: 7-81071-935-1. 5. 余家阔副主编.见刘玉杰主编《膝关节韧带损伤修复与重建》. 主编:刘玉杰,敖英芳,陈世益. 副主编:薛静,余家阔,孙磊. 人民卫生出版社. 2008年第一版. I S B N :978-7-117-10723-5. Associate Editor-in-Chief: Jia-Kuo Yu. Repair and Reconstruction of Knee Ligament Injuries, edited by Liu Yujie, Ao Yingfang, and Chen Shiyi. Associate Editors: Xue Jing, Jia-Kuo Yu, and Sun Lei. People's Medical Publishing House: First Edition, 2008. ISBN: 978-7-117-10723-5. 6. 余家阔副主编. 见敖英芳主编《运动创伤手术操作与技巧》. 副主编:胡跃林,崔国庆,余家阔,王健全. 2008年1月第一版. 北京:人民卫生出版社. 40.2万字. I S B N:978-7-117-09616-4. Associate Editor-in-Chief: Jia-Kuo Yu. Surgical Operations and Techniques in Sports Injuries, edited by Ao Yingfang. Associate Editors: Hu Yuelin, Cui Guoqing, Jia-Kuo Yu, and Wang Jianquan. People's Medical Publishing House: First Edition, January 2008. 402,000 characters. ISBN: 978-7-117-09616-4. 7. 余家阔副主编. 见关骅和张光铂主编《中国骨科康复学》. 副主编:余家阔,郭险峰,洪毅,郭龙. 人民军医出版社. 2011年5月第一版. 133万字. 北京. I S B N:978-7-5091-4364-3. Associate Editor-in-Chief: Jia-Kuo Yu. Chinese Orthopedic Rehabilitation, edited by Guan Hua and Zhang Guangbo. Associate Editors: Jia-Kuo Yu, Guo Xianfeng, Hong Yi, and Guo Long. People's Military Medical Publishing House: First Edition, May 2011. 1,330,000 characters. Beijing. ISBN: 978-7-5091-4364-3. 8. 余家阔副主编. 见敖英芳主编《关节镜外科学》. 副主编:胡跃林,余家阔,徐国庆,王健全. 北京大学医学出版社. 国家十一五重点图书. 2012年9月第一版. 128.6万字. I S B N:978-7-5659-0400-4. Associate Editor-in-Chief: Jia-Kuo Yu. Arthroscopic Surgery, edited by Ao Yingfang. Associate Editors: Hu Yuelin, Jia-Kuo Yu, Xu Guoqing, and Wang Jianquan. Peking University Medical Press: National Eleventh Five-Year Plan Key Book. First Edition, September 2012. 1,286,000 characters. ISBN: 978-7-5659-0400-4. 9. 余家阔副主编. 见刘玉杰主编《膝关节韧带损伤修复与重建》(第二版).主编:刘玉杰,敖英芳,陈世益. 副主编:孙磊,余家阔,薛静,王俊良. I S B N :978-7-117-18499-1. 人民卫生出版社. 2014年5月第二版. Associate Editor-in-Chief: Jia-Kuo Yu. Repair and Reconstruction of Knee Ligament Injuries (Second Edition), edited by Liu Yujie, Ao Yingfang, and Chen Shiyi. Associate Editors: Sun Lei, Jia-Kuo Yu, Xue Jing, and Wang Junliang. People's Medical Publishing House: Second Edition, May 2014. ISBN: 978-7-117-18499-1. 10. 余家阔副主译. 见韩鸿宾等主译:《骨骼肌肉MRI/CT断层解剖(第四版)》. 原著:Mark W. Anderson, Michael G.Fox主编《Sectional anatomy by MRI and CT》. 副主译:张卫光,余家阔,王福生,阎军浩. 2019年6月第四版. 1210千字. 北京:北京大学医学出版社. ISBN:978-7-5659-1759-2. Associate Translator-in-Chief: Jia-Kuo Yu. Sectional Anatomy by MRI and CT (Fourth Edition), translated by Han Hongbin et al. Associate Translators: Zhang Weiguang, Jia-Kuo Yu, Wang Fusheng, and Yan Junhao. Originally authored by Mark W. Anderson and Michael G. Fox. Fourth Edition, June 2019. 1,210,000 characters. Peking University Medical Press. ISBN: 978-7-5659-1759-2. 11. 余家阔副主编. 见国家体育总局冬季运动管理中心编著《中国冰雪项目运动伤病防治—国家队队医培训教材》. 主编:崔国庆. 副主编:谢敏豪,余家阔,胡跃林,庞晓峰,李璟,王天兵,矫玮,周方,张辛,常翠青,罗浩. 2022年1月第一版. 622千字. 北京:中国计划出版社. I S B N:978-7-5182-1380-1. Associate Editor-in-Chief: Jia-Kuo Yu. Prevention and Treatment of Sports Injuries in China's Winter Sports Programs - Training Textbook for National Team Doctors. Edited by Cui Guoqing. Associate Editors: Xie Minhao, Jia-Kuo Yu, Hu Yuelin, Pang Xiaofeng, Li Jing, Wang Tianbing, Jiao Wei, Zhou Fang, Zhang Xin, Chang Cuiqing, and Luo Hao. First Edition, January 2022. 622,000 characters. Beijing: China Planning Press. ISBN: 978-7-5182-1380-1. 12. 余家阔副主编. 见邱贵兴等主编《骨骼肌肉现代康复学》(上册).主编:邱贵兴,洪毅,唐佩福,蒋协远. 副主编:刘克敏,张军卫,余家阔,陈亚平,刘宝戈,姚浩群,苏彦农,郭险峰,姜春岩,崔国庆,陈学明,赵宇. I S B N :15BN978-7-80237-9466. 1856千字,73印张. 军事科学出版社. 2023年7月第一版. Associate Editor-in-Chief: Jia-Kuo Yu. Modern Rehabilitation of Musculoskeletal System (Upper Volume), Edited by Qiu Guixing, Hong Yi, Tang Peifu, and Jiang Xieyuan. Associate Editors: Liu Kemin, Zhang Junwei, Jia-Kuo Yu, Chen Yaping, Liu Baoge, Yao Haoqun, Su Yannong, Guo Xianfeng, Jiang Chunyan, Cui Guoqing, Chen Xueming, and Zhao Yu. ISBN: 978-7-80237-9466. 1,856,000 characters, 73 printed sheets. Military Science Press: First Edition, July 2023. 13. 余家阔副主编. 见邱贵兴等主编《骨骼肌肉现代康复学》(下册).主编:邱贵兴,洪毅,唐佩福,蒋协远. 副主编:刘克敏,张军卫,余家阔,陈亚平,刘宝戈,姚浩群,苏彦农,郭险峰,姜春岩,崔国庆,陈学明,赵宇. I S B N :15BN978-7-80237-9466. 1856千字,73印张. 军事科学出版社. 2023年7月第一版. Associate Editor-in-Chief: Jia-Kuo Yu. Modern Rehabilitation of Musculoskeletal System (Lower Volume), Edited by Qiu Guixing, Hong Yi, Tang Peifu, and Jiang Xieyuan. Associate Editors: Liu Kemin, Zhang Junwei, Jia-Kuo Yu, Chen Yaping, Liu Baoge, Yao Haoqun, Su Yannong, Guo Xianfeng, Jiang Chunyan, Cui Guoqing, Chen Xueming, and Zhao Yu. ISBN: 978-7-80237-9466. 1,856,000 characters, 73 printed sheets. Military Science Press: First Edition, July 2023. |
获奖和荣誉 |
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1. 余家阔荣获美国中华医学基金会-北京医科大学的1998年杰出青年学者奖。1998年12月28日 Jia-Kuo Yu was awarded the 1998 Outstanding Young Scholar Award by the China Medical Board-Peking Medical University on December 28, 1998. 2. 余家阔荣获德国Rastatt术者和机器人ACL重建比赛优胜奖。胜方主刀:Hans. H. Paessler,胜方手术助手:余家阔。比赛主办方:RICHARD WOLF企业和ORTO MAQUET企业。2000年12月08日 Jia-Kuo Yu won the Rastatt Operator-Robot ACL Reconstruction Competition in Germany. The winning surgeon was Hans H. Paessler, and the winning surgical assistant was Jia-Kuo Yu. The competition was sponsored by RICHARD WOLF and ORTO MAQUET on December 8, 2000. 3. 余家阔荣获第二十八届雅典奥运会“集体奥运特别贡献奖”成员。中华人民共和国国家体育总局2004年12月。 Jia-Kuo Yu was a member of the team awarded the "Collective Olympic Special Contribution Award" at the 28th Athens Olympic Games by the General Administration of Sport of China in December 2004. 4. 余家阔获中华人民共和国卫生部国际交流与合作中心评选的第九届“吴阶平医学研究奖-保罗·扬森药学研究奖”运动医学专业二等奖. 2006年10月16日。 Jia-Kuo Yu received the second prize in Sports Medicine at the 9th Wu Jieping Medical Research Award – Paul Janssen Pharmaceutical Research Award, selected by the International Exchange and Cooperation Center of the Ministry of Health of the People's Republic of China on October 16, 2006. 5. 余家阔被授予北京大学医学部“2012-2014年度优秀人才奖励计划二等奖”。 奖励期限为三年,自2012年1月至2014年12月。 Jia-Kuo Yu was granted the "2012-2014 Outstanding Talent Incentive Plan Second Prize" by the Peking University Health Science Center. The award period was three years, from January 2012 to December 2014. 6. 余家阔荣获国家体育总局第三十届奥运会科技奖励. 第三十届奥运会科研攻关与科技服务突出贡献个人奖。 2013年8月5日. 全国共50人, 北医三院余家阔入选。 Jia-Kuo Yu was awarded the 30th Olympic Games Science and Technology Award by the General Administration of Sport of China. He received the Individual Award for Outstanding Contribution to Scientific Research and Technological Services for the 30th Olympic Games on August 5, 2013. Among 50 recipients nationwide, Jia-Kuo Yu was the only one from Peking University Third Hospital. 7. 余家阔荣获2016年度北京大学医学部优秀奖:“2016年度北京大学医学部优秀教师”荣誉称号。北京大学医学部,2016年9月8日。 Jia-Kuo Yu was honored with the "2016 Outstanding Teacher Award" by the Peking University Health Science Center on September 8, 2016. 8. 余家阔荣获北京大学医学部优秀教师荣誉称号,2016年9月。 Jia-Kuo Yu was awarded the title of Outstanding Teacher by the Peking University Health Science Center in September 9, 2016. 9. 余家阔荣获2021年北京大学医学部教学优秀奖. 2021年9月9日。 Jia-Kuo Yu received the Teaching Excellence Award Peking University Health Science Center on September 9, 2021. 10. 余家阔. 荣获“北京大学第五届产学研项目合作先进个人”奖.。北京大学2021年5月4日。 Jia-Kuo Yu was awarded the "Fifth Peking University Outstanding Individual in Industry-University-Research Collaboration" by Peking University on May 4, 2021. 11. 余家阔荣获2022年度“北京大学2022年度仲外医学奖”。北京大学和中共北京大学委员会。2022年4月9日。2013年2月28日,日本中外制药株式会社向北京大学医学部捐赠人民币210万元,设立“北京大学仲外医学基金”。基金主要用于以中外医学奖的形势,奖励优秀医学人才以及医学生奖学金。中外制药株式会社于1925年3月在东京成立。是一家主要在癌症、骨关节和肾脏领域的研究开发型制药企业。 Jia-Kuo Yu was awarded the 2022 "Zhongwai Medical Award" by Peking University and the Communist Party Committee of Peking University on April 9, 2022. On February 28, 2013, Chugai Pharmaceutical Co., Ltd. donated RMB 2.1 million to Peking University Health Science Center to establish the "Peking University Chugai Medical Fund." The fund primarily rewards outstanding medical talents and provides scholarships for medical students through the Chugai Medical Award. Chugai Pharmaceutical Co., Ltd. was founded in Tokyo in March 1925 and is a research-driven pharmaceutical company focusing on cancer, bone and joint, and kidney diseases. 12. 余家阔荣获北京市首届先进科技工作者称号。2023年7月1日。 Jia-Kuo Yu was awarded the title of Beijing's First Advanced Science and Technology Worker on July 1, 2023. 13. 余家阔荣获2024年度清华大学附属北京清华长庚医院“年度医师”奖。2024年8月19日。 Jia-Kuo Yu was awarded the "Annual Physician Award" by Beijing Tsinghua Changgung Hospital, affiliated with Tsinghua University, on August 19, 2024. |
主要兼职 |
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1. 2025年1月20日至今:清华大学附属北京清华长庚医院(清华大学临床医学院)学术委员会副主席 Jan. 20, 2025 - Present: Vice Chairman, Academic Committee, Beijing Tsinghua Changgong Hospital,School of Clinical Medicine, Tsinghua University 2. 2024年12月20日至今:清华大学长聘教授委员会医学组委员 Dec. 20, 2024 – Present: Member of medical group, tenured professor evaluation committee, Tsinghua University 3. 2024年9月28日至今:中国老年学和老年医学分会第七届理事会常务理事 From September 28, 2024 to present: Executive Director of the Seventh Council of the China Association of Gerontology and Geriatrics 4. 2024年6月8日至今:清华大学医学院教学委员会委员 From June 8, 2024 to present: Member of the Teaching Committee of School of Medicine , Tsinghua University 5. 2024年6月8日至今: 清华大学医学院教学委员会的委员 Jun. 8, 2024 – Present: Member of the Teaching Committee, School of Clinical Medicine, Tsinghua University 6. 2024年4月3日至今:清华大学临床医学院长聘教授委员会委员 Apr. 3, 2024 - Present: Member of the Tenured Professor Committee, School of Clinical Medicine, Tsinghua University 7. 2023年11月1日至今:中国运动医学杂志副主编 From November 1, 2023 to present: Deputy Editor-in-Chief of the Chinese Journal of Sports Medicine 8. 2023年9月14日至今:中华人民共和国科技部 “十四五”国家重点研发计划增材制造领域总体专家组专家 From September 14, 2023 to present: Expert of the Overall Expert Group in the field of Additive Manufacturing for the "14th Five-Year Plan" National Key Research and Development Program,Ministry of Science and Technology of the People's Republic of China. 9. 2023年5月19日至今:中华医学会运动医疗分会常委 From May 19, 2023 to present: Standing Committee Member of the Sports Medicine Branch of the Chinese Medical Association 10. 2023年至今:中华骨与关节外科杂志常务编委 From 2023 to present: Executive Editor of the Chinese Journal of Bone and Joint Surgery 11. 2022年04月-2027年04月:中国老年医学学会运动健康分会副会长 From April 2022 to April 2027: Vice President of the Sports Health Branch of China Association of Gerontology and Geriatrics 12. 2021年05月至今,中国医师协会骨科医师分会运动医学学组副组长 From May 2021 to present: Vice Chairman of the Sports Medicine Group of the Orthopedic Surgeons Branch of the Chinese Medical Doctor Association 13. 2020年12月-2025年12月:中国田径协会运动健康专家评聘工作组副组长 From December 2020 to December 2025: Vice Chairman of the Sports Health Expert Evaluation Working Group of the China Athletic Association 14. 2020年09月-2025年09月:白求恩精神研究会矫形分会第一届理事会名誉会长 From September 2020 to September 2025: Honorary President of the first Council of the Orthopedic Branch of the Bethune Spirit Research Society 15. 2020年04月至今:《中国矫形外科杂志》第五届编委会关节镜与运动医学主编 From April 2020 to present: Editor-in-Chief of Arthroscopy and Sports Medicine for the fifth editorial board of the "Chinese Orthopedic Journal" 16. 2020年至2024年:中国修复重建外科杂志编委 From 2020 to 2024: Member of the editorial board of the Chinese Journal of Reparative and Reconstructive Surgery 17. 2019年11月至今:中国生物材料学会生物材料先进制造分会副主任委员 From November 2019 to present: Vice Chairman of the Advanced Manufacturing Branch of the Chinese Society for Biomaterials 18. 2019年06月至今:全国外科植入物和矫形器械标准化技术委员会运动医学专家组副主任委员 From June 2019 to present: Vice Chairman of the Sports Medicine Expert Group of the National Technical Committee on Standardization for Surgical Implants and Orthopedic 19. 2019年07月至今 :中国研究型医院学会运动医学专业委员会副主任委员 From July 2019 to present: Vice Chairman of the Sports Medicine Professional Committee of the Chinese Research Hospital Association 20. 2019年06月至今 :中国医药教育协会肩肘运动医学冬季运动损伤分会副主委 From June 2019 to present: Vice Chairman of the Shoulder and Elbow Winter Sports Injury Branch of the China Medical Education Association 21. 2019年01月至今 :中华人民共和国国务院 享受国务院政府特殊津贴专家 From January 2019 to present: Expert entitled to special government allowance from the State Council of the People's Republic of China 22. 2019年12月至今:中国老年学和老年医学学会老年运动医学分会创始主委 From December 2019 to present: Founding Chairman of the Geriatric Sports Medicine Branch of China Association of Gerontology and Geriatrics 23. 2018年10月~2023年5月19日:中华医学会运动医疗分会副主任委员 From October 2018 to May 19, 2023: Vice Chairman of the Sports Medicine Branch of the Chinese Medical Association 24. 2017年02月至今:中国研究型医院学会关节外科学组副组长 From February 2017 to present: Vice Chairman of the Joint Surgery Group of the Chinese Research Hospital Association 25. 2017年03月至今:国家药品监督管理局医疗器械分类技术委员会无源植入物组长 From March 2017 to present: Chairman of the Passive Implants Group of the Medical Device Classification Technical Committee of the National Medical Products Administration 26. 2016年11月至今:中国共产党中央委员会中央保健委员会中央保健会诊专家 From November 2016 to present: Expert Consultant of the Central Health Consultation Committee of the CPC Central Committee 27. 2015年11月至今:中国残疾人康复协会运动损伤重建与康复学组副主任委员 From November 2015 to present: Vice Chairman of the Sports Injury Reconstruction and Rehabilitation Group of the China Association of Rehabilitation of Disabled Persons 28. 2015年5月至今:中国微创外科杂志常务编委 From May 2015 to present: Executive Editor of the Chinese Journal of Minimally Invasive Surgery 29. 2013年至今:中华创伤骨科杂志编委 From 2013 to present: Member of the editorial board of the Chinese Journal of Traumatology 30. 2013年至今:中华骨科杂志编委 From 2013 to present: Member of the editorial board of the Chinese Journal of Orthopedics 31. 2009年至今:中国骨科临床与基础研究杂志编委 From 2009 to present: Member of the editorial board of the Chinese Journal of Clinical and Basic Orthopaedics |